Lead poisoning and asthma: an examination of comorbidity.
نویسندگان
چکیده
OBJECTIVES To determine the comorbidity of lead poisoning and asthma in urban children, and to examine associated clinical factors. METHODS One-hundred-one patients at an inner-city clinic with blood lead levels (BLLs) of 25 microg/dL or higher (> or =1.2 micromol/L) (BLL25 group) were randomly selected from a tracking lead database and matched on age, sex, and primary language to 101 randomly selected patients with a first BLL recorded in the database of lower than 5 microg/dL (<0.2 micromol/L) (BLL5 group) and no subsequent BLLs of 10 microg/dL or higher (> or =0.5 micromol/L). Medical records were reviewed to determine diagnosis or symptoms of asthma or wheezing at any visit, immunization status, and number of visits. Analyses for matched pairs were conducted. RESULTS The BLL25 and BLL5 groups did not differ on age at diagnostic BLL (26.6 months vs 24.2 months), sex (54% male), or language (12% Spanish). The BLL25 and BLL5 groups had a similar number of subjects with a diagnosis of asthma (6% vs 11%; odds ratio, 0.5; 95% confidence interval, 0.2-1.6); 26% of BLL25 and 34% of BLL5 subjects had either a diagnosis or symptoms of asthma or wheezing (odds ratio, 0.7; 95% confidence interval, 0.4-1.3). Subjects with BLL25 were more likely to have delayed immunization and a first clinic visit when older than subjects with BLL5. CONCLUSIONS There was no increased likelihood of asthma diagnosis or symptoms among young children with lead poisoning. Children with lead poisoning also had delayed medical care. These data may help guide interventions aimed at preventing or reducing the impact of lead poisoning and asthma.
منابع مشابه
The Relationship of Housing and Population Health: A 30-Year Retrospective Analysis
OBJECTIVE We analyzed the relationship between health status and housing quality over time. METHODS We combined data from two nationally representative longitudinal surveys of the U.S. population and its housing, the National Health and Nutrition Examination Survey and the American Housing Survey, respectively. We identified housing and health trends from approximately 1970 to 2000, after exc...
متن کاملBlood Lead Level and Risk of Asthma
Asthma and lead poisoning are prevalent among urban children in the United States. Lead exposure may be associated with excessive production of immunoglobulin E, possibly increasing asthma risk and contributing to racial disparities. The objective of this study was to examine racial differences in the association of blood lead level (BLL) to risk of developing asthma. We established and followe...
متن کاملهمراهی سطح سرب خون ساکنین شهر اراک با سندرومهای بالینی
Background: The presence of lead in the industrial fumes, sewage, and also in industrial paints, ceramic, and printing materials, make this element as one of the most common environmental contaminant. Lead can enter the body through respiratory and digestive tracts as well as through the skin and with progressive accumulation can have a destructive effect on several organs in the human body. Bl...
متن کاملLead Poisoning in an Infant: A Case Report
There is inadequate knowledge about acute poisoning as a common problem in children. Acute poisoning in children, , is one of the health problems, requiring immediate treatment. Case report: A two-month-old male infant with discoloration of the nails was admitted to the Emergency Pediatric Unit of Imam Reza Hospital, Mashhad, Iran in 2014. Following clinical evaluations, the blood lead level w...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Archives of pediatrics & adolescent medicine
دوره 156 9 شماره
صفحات -
تاریخ انتشار 2002